Erja Forssas1*, Reijo Sund1, Kristiina Manderbacka1, Martti Arffman1, Pirjo Ilanne-Parikka2 and Ilmo Keskimäki1

Jian Zhang (zhangjian890@126.com) Xia Wan Xiao (xiaowanxia2005@163.com) Feng Yuan Zhu (349276797@qq.com) Said Fatuma Muhali (muhalifatma@yahoo.co.uk) Ling Xiao (xl77215@163.com) Juan Wen Jiang (hidyfan81@yahoo.com.cn) Hong Xiao Shi (jjzhao@medmail.com.cn) Hua Lian Zhou (zhoulianhua@medmail.com.cn) An Jin Zhang (zhangjinan@hotmail.com)

Thomas Larsen1,2*, Frank H Mose1,2, Jesper N Bech1,2 and Erling B Pedersen1,2

Tetine L. Sentell, PhD; Hyeong Jun Ahn, PhD; Deborah T. Juarez, ScD; Chien-Wen Tseng, MD; John J. Chen, PhD; Florentina R. Salvail, MSc; Jill Miyamura, PhD; Marjorie L.M. Mau, MD

MARYAM SADAT MIRAGHAJANI, MSC1,2 AHMAD ESMAILLZADEH, PHD1,2 MOJGAN MORTAZAVI NAJAFABADI, MD3

MARYAM MIRLOHI, PHD1,4 LEILA AZADBAKHT, PHD1,2

PING ZHANG, PHD1 MORTON B. BROWN, PHD2 DORI BILIK, MBA3

RONALD T. ACKERMANN, MD4 RUI LI, PHD1 WILLIAM H. HERMAN, MD, MPH3

CLAUDIO TIBERTI, ACD1 FRANCESCA PANIMOLLE, BS1 MARGHERITA BONAMICO, MD2 BLEGINA SHASHAJ, MD2 TIZIANA FILARDI, MD1

FEDERICA LUCANTONI, BS2 RAFFAELLA NENNA, MD2 FRANCESCO COSTANTINO, MD2 ANDREA LENZI, MD3

SUSANNA MORANO, MD1

CHARLOTTE ANDERSSON, MB1 GUNNAR H. GISLASON, MD, PHD1 CHARLOTTE MÉRIE, MD1 ULRIK M. MOGENSEN, MB2

ANA LÓPEZ-DE-ANDRÉS, PHD, MPH MARÍA A. MARTÍNEZ-HUEDO, MD PILAR CARRASCO-GARRIDO, PHD, MPH

VALENTIN HERNÁNDEZ-BARRERA, MD ÁNGEL GIL-DE-MIGUEL, MD, PHD RODRIGO JIMÉNEZ-GARCÍA, MD, PHD

Maja Stefanovic-Racic,1 Xiao Yang,1 Michael S. Turner,2 Benjamin S. Mantell,1 Donna B. Stolz,3,4 Tina L. Sumpter,5 Ian J. Sipula,1 Nikolaos Dedousis,1 Donald K. Scott,1 Penelope A. Morel,2 Angus W. Thomson,2,5 and Robert M. O’Doherty1