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Prognostic Significance of Ankle-Brachial Index, Brachial-Ankle Pulse Wave Velocity, Flow-Mediated Dilation, and Nitroglycerin-Mediated Dila
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| 09.03.2009, 22:12 |
Background: Identifying patients at high risk of cardiovascular
disease is important in managing patients undergoing
hemodialysis. Methods: We evaluated a series of prognostic
values: flow-mediated dilation (FMD) and nitrogen-mediated
dilation (NMD), an index of endothelium-dependent and
endothelium-independent function, respectively, anklebrachial
index (ABI), and brachial-ankle pulse wave velocity
(baPWV) in patients undergoing chronic hemodialysis. Results:
A cohort of 199 patients was studied. At entry, these
values were examined and the prognostic significances
were investigated. In estimating the significance of baPWV,
patients with ABI ! 0.9 were excluded. During the follow-up
period, 24 deaths occurred including 14 cardiovascular and
10 noncardiovascular fatal events. Overall, the survival rates
were significantly lower in the low ABI than in the high ABI
group, but the survival rates were not significantly different
between the high and low FMD, NMD, or baPWV groups.
Cardiovascular survival rates were significantly lower in the
low ABI than in the high ABI group, and in the high baPWV.
Background: Identifying patients at high risk of cardiovascular
disease is important in managing patients undergoing
hemodialysis. Methods: We evaluated a series of prognostic
values: flow-mediated dilation (FMD) and nitrogen-mediated
dilation (NMD), an index of endothelium-dependent and
endothelium-independent function, respectively, anklebrachial
index (ABI), and brachial-ankle pulse wave velocity
(baPWV) in patients undergoing chronic hemodialysis. Results:
A cohort of 199 patients was studied. At entry, these
values were examined and the prognostic significances
were investigated. In estimating the significance of baPWV,
patients with ABI ! 0.9 were excluded. During the follow-up
period, 24 deaths occurred including 14 cardiovascular and
10 noncardiovascular fatal events. Overall, the survival rates
were significantly lower in the low ABI than in the high ABI
group, but the survival rates were not significantly different
between the high and low FMD, NMD, or baPWV groups.
Cardiovascular survival rates were significantly lower in the
low ABI than in the high ABI group, and in the high baPWV.
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Категория: Статьи | Добавил: nbylova
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